Background:

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter.

Applications:

WB

Name of antibody:

MAP2K3(Ab-222)

Immunogen:

Synthesized non-phosphopeptide derived from human MAP2K3 around the phosphorylation site of threonine 222 (A-K-T(p)-M-D).

Full name:

mitogen-activated protein kinase kinase 3

Synonyms：

MEK3; MKK3; MAPKK3; PRKMK3; SAPKK2; SAPKK-2

SwissProt:

P46734

WB Predicted band size:

39 kDa

WB Positive control:

Jurkat cells treated with serum (20%, 15mins) lysate

WB Recommended dilution:

500-3000