Background:

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival.

Applications:

WB

Name of antibody:

PIN1(Phospho-Ser16)

Immunogen:

Peptide sequence around phosphorylation site of serine16(R-M-S(p)-R-S) derived from Human Pin1 .

Full name:

peptidylprolyl cis/trans isomerase, NIMA-interacting 1

Synonyms：

DOD; UBL5

SwissProt:

Q13526

WB Predicted band size:

18 kDa

WB Positive control:

COS7 cells lysates treated with Insulin

WB Recommended dilution:

500-1000